Daily Power Defense has been elevated with ZO’s exclusive technologies – including new ZPOLY™ complex – to enable a long-lasting, youthful and healthy skin complexion. This advanced serum is clinically proven to strengthen skin’s protective barrier while defending against environmental stressors and premature signs of aging. Seller Note: Like new, no box. I bought the entire regime and and tried it once. (1 pump max.) The ingredients in these products can not be used with a medication I am on which is the ONLY reason I don’t continue use. These are top quality ingredients! Make me an offer!