A Smarter Way To Retinol. Phyto-Retinol Sleep Serum is powered by Peptilium®, clinically proven to work 2X faster and better than traditional retinol without the sensitizing side effects. This is a natural skincare product, sometimes there are variations in consistency or texture. Please contact me first if you have any questions on a product you receive. I will check in the stores I work in as well as the brand to confirm variations. These are all new in box or original packaging.