New Never Used comes in box not sealed SkinBetter AlphaRet Overnight Cream features a unique ingredient that is made up of a retinoid combined with an alpha hydroxy acid (AHA) that may provide visible skin rejuvenation with little-to-no irritation. It may improve the appearance of lines, wrinkles, uneven tone and texture. AlphaRet significantly reduces the appearance of wrinkles in as little as four weeks, with little-to-no irritation and provides moisture to help counteract dryness associated with traditional retinoid-based products.