New/open. die Falco stars as title character Jackie Peyton, a drug-addicted emergency room nurse in a New York City hospital. For Jackie, every day is a high-wire act of juggling patients, doctors, fellow nurses and her own indiscretions. The second season of the Showtime Original Series Nurse Jackie™ continues its look deep inside the complicated heart and soul of a functioning addict, a loving wife and mother, and a first-class nurse.