Nike Epic React Flyknit 2 Mens Lime Blast Running Shoes The Nike Epic React Flyknit 2 takes a step up from its predecessor with smooth, lightweight performance and a bold look. An updated Flyknit upper conforms to your foot with a minimal, supportive design. Underfoot, durable Nike React technology defies the odds by being both soft and responsive, for comfort that lasts as long as you can run.