Retinoids for Face: For smooth, youthful, healthy-looking skin, the groundbreaking formula is powered by three skin-renewing retinoids – granactive retinoid (R), and encapsulated pure retinol and retinal – plus a collagen-boosting polypeptide. Skin Barrier Repair: Fortified with niacinamide, bisabolol, ceramides, and beetroot extract, the serum also helps repair barrier function and calm skin to minimize irritation while delivering a continuous dose of moisture. Anti-Wrinkle: To turn back the clock on the look of deep wrinkles, lines, rough texture, laxity, and dull skin, and more, this is the nightly serum for renewed skin. For p.m. use only: Smooth the retinol serum over cleansed face and neck, avoiding the eye area. Limit initial use to three times a week, gradually increasing frequency to every night as tolerated. Clinical Study Results*: In just 4 weeks, 100% showed improvement in the look of deep wrinkles. 100% showed improvement in the look of facial pores. 100% showed improvement in hydration. *Based on an eight-week clinical study of 32 subjects aged 35-70.